Homocysteine Cardioplex 90 caps

Maintains homocysteine levels for optimal cardiovascular well-being

Key Ingredients

Quatrefolic^®: 

A reduced and active form of folate (vitamin B-9), Quatrefolic, the advanced 5-methyltetrahydrofolate (5 MTHF) form, is bound with natural glucosamine salt to promote easy and complete absorption. Considered the “Fourth Generation” folate, Quatrefolic is significantly more stable and bioavailable than 5 MTHF that is bound to calcium salt. Because Quatrefolic is active when it enters the body, it is better able to influence pathways for homocysteine metabolism. Quatrefolic’s pre-converted status may be especially beneficial for patients with a genetic defect of the folate-converting enzyme methylentetrahydrofolate reductase. 

Vitamins B-6 and B-12:

Supplying vitamins B-6 (as pyridoxal-5-phosphate) and B-12 (as methylcobalamin), Homocysteine Cardioplex provides two extensively researched clinical standards for nutritional homocysteine management. B-6 modulates homocysteine’s conversion into cystathione, a key step in its excretion. B-12 is an important donor for enabling homocysteine to be remethylated into methionine. B-12 also works in concert with the coenzyme methionine synthase, creating a primary pathway of remethylation of homocysteine.

N-Acetyl L-Cysteine (NAC):

A free-form amino acid, N-Acetyl L-Cysteine (NAC) is believed to block homocysteine formation at plasma protein binding sites while encouraging efficient elimination of homocysteine via urinary excretion. Studies have suggested NAC appears to be especially beneficial in promoting healthy homocysteine levels in patients who have undergone kidney transplants. As it works to promote healthy endothelial function, NAC offers further support for overall cardiovascular wellness.

Trimethylglycine (as betaine anhydrous):

Trimethylglycine, also known as betaine, is considered a key player in homocysteine metabolism and has long been administered as a methyl donor for remethylating homocysteine back into methionine. Trimethylglycine (TMG) betaine is a necessary cofactor in the secondary pathway of homocysteine metabolism. Betaine is typically administered to patients who are not responsive to pyridoxine (B-6) and other B vitamins.

Magnesium as TRAACS^®:

An acronym for The Real Amino Acid Chelate System, TRAACS is a patented range of proprietary mineral amino acid chelates. TRAACS magnesium (Magnesium Glycinate Chelate Buffered Powder) is an organic mineral form known for its safety and ease of absorption. Featuring a biological advantage in assimilation, TRAACS requires no conversion: It is an active cofactor for promoting efficient homocysteine-to-methionine conversion. Early research also suggests magnesium may support arterial health and play a role in modulating production of the destructive MMP-2 enzyme, which has been linked with homocysteine issues and collagen degradation.